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Astragalus polyphenols

CAS No. 82373-94-2

Astragalus polyphenols( —— )

Catalog No. M19145 CAS No. 82373-94-2

Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Astragalus polyphenols
  • Note
    Research use only, not for human use.
  • Brief Description
    Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.
  • Description
    Astragalus polyphenols is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.
  • In Vitro
    Western Blot Analysis Cell Line:RAW264.7 cells Concentration:5-80 μM Incubation Time:2 h Result:Reduced the phosphorylation level of ERK2, IκBα, IKKβ, and NF-κB p65 in a dosedependent manner.Attenuated LPS-induced nuclear translocation with a dose-dependent behavior.
  • In Vivo
    Animal Model:Male ICR miceDosage:30-60 mg/kg Administration:i.p., daily, 7 days Result:Inhibited the production of proinflammatory cytokines induced by LPS, such as interleukin-1β, interleukin-6, and tumor necrosis factor-α.Prevented the LPS-induced enhancement of oxido-nitrosative stress in mouse hippocampus and prefrontal cortex.Prevented LPS-induced decreases in brain-derived neurotrophic factor levels in the hippocampus and prefrontal cortex.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Others
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    82373-94-2
  • Formula Weight
    406.38
  • Molecular Formula
    C20H22O9
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 35 mg/mL; 86.13 mM
  • SMILES
    [C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)Oc1c(/C=C/c2ccc(cc2)O)cc(cc1O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ma ZJ, et al. Zhongguo Zhong Yao Za Zhi. 2015 Jun;40(12):2325-9.
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